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      https://www.ias.ac.in/article/fulltext/boms/038/01/0259-0266

    • Keywords

       

      Biphasic calcium phosphate; bone graft; Cassia occidentalis; simulated body fluid; SaOS-2 cell line.

    • Abstract

       

      Research on traditional herbs is gaining momentum owing to their potent medical properties, among which Cassia occidentalis (CO) is a promising herb, with osteogenic potential. The study investigates the efficacy of CO extract incorporated biphasic calcium phosphate as an osteoinductive material. Prepared bone implants were characterized physico-chemically using FT-IR, TGA, XRD, SEM and EDX. The implants were analysed further for mechanical and biological properties. The results revealed that CO extract-incorporated bone implants possessed better compression strength and it was able to induce proliferation and enhance alkaline phosphatase activity in SaOS-2 cells. The implant proves to be promising for bone tissue engineering, and hence it demands further in vivo evaluation.

    • Author Affiliations

       

      B Santhosh Kumar1 T Hemalatha1 R Deepachitra1 R Narasimha Raghavan1 P Prabu1 T P Sastry1

      1. Bioproducts Laboratory, Central Leather Research Institute, Adyar, Chennai 600 020, India
    • Dates

       
  • Bulletin of Materials Science | News

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