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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/boms/036/02/0329-0332

    • Keywords

       

      Surfactant; reverse micellar method; silica mesostructures; surface area.

    • Abstract

       

      The encapsulation of biomolecules in inert meso or nanostructures is an important step towards controlling drug delivery agents. Mesoporous silica nanoparticles (MSN) are of immense importance owing to their high surface area, large pore size, uniform particle size and chemical inertness. Reverse micellar method with CTAB as the surfactant has been used to synthesize anisotropic mesoporous silica materials. We have used the anisotropic silica nanostructures for DNA encapsulation studies and observed a loading capacity of ∼8 𝜇g mg-1 of the sample. On functionalizing the pores of silica with amine group, the amount of DNA loaded on the rods decreases which is due to a reduction in the pore size upon grafting of amine groups.

    • Author Affiliations

       

      Aparna Ganguly1 Ashok K Ganguli1

      1. Department of Chemistry, Indian Institute of Technology, HauzKhas, New Delhi 110 016, India

    • Dates

       
      Published
      April 2013
      Manuscript received
      28 March 2012

  • Bulletin of Materials Science | News

    • Dr Shanti Swarup Bhatnagar for Science and Technology

      Posted on October 12, 2020

      Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
      Chemical Sciences 2020

      Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
      Physical Sciences 2020

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

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