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    • Keywords


      Anti-tumor activity; self-charged; nanoparticles.

    • Abstract


      Non-stoichiometric (Eu,Ca):WO3 and Eu:CaWO4 nanoparticles with anti-tumor activity are synthesized in a sol–gel method by adding excessive Eu3+ and Ca2+ ions to tungsten oxide crystal structure. Colorimetric assay shows that 10 nm (Eu,Ca):WO3 and Eu:CaWO4 nanoparticles can effectively inhibit growth of mammary cancer cells without any harm to normal cells. Nanoparticles are characterized by X-ray diffraction, high resolution transmission electron microscopy and fluorescence optical spectrometry. Nanomaterials, insoluble in synthesized water, have complicated self-charging surfaces that trap mammary cancer cells. Surface self-charging effect is suggested as the inhibition mechanism.

    • Author Affiliations


      Cao Lin1 Cao Jiexin2 Wang Cong1 Che Ping3 Pan De’an1 Alex A Volinsky4

      1. Department of Materials Physics, University of Science and Technology Beijing, Beijing 100083, China
      2. Peking University Health Science Centre, Beijing 100191, China
      3. School of Applied Science, University of Science and Technology Beijing, Beijing 100083, China
      4. Department of Mechanical Engineering, University of South Florida, Tampa FL 33620, USA
    • Dates

  • Bulletin of Materials Science | News

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    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

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