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    • Keywords


      Hydroxyapatite; biomaterials; sintering; tissue engineering; cytotoxicity.

    • Abstract


      In the present study, hydroxyapatite (HAp) is synthesized from different biosources like eggshell, fish scale and bovine bone in a cost effective and ecofriendly way. HAp materials were synthesized from eggshell by wet precipitation method whereas thermal decomposition method was applied in case of fish scale and bovine bone. The phase purity and crystallinity of different calcined HAp powder were determined by XRD and FTIR analyses. The thermogravimetric analysis was carried out to show thermal stability of HAp powder. Average grain sizes of sintered samples were in submicron range. The morphology of the powders were observed under scanning electron microscopy (SEM). The dried powders were wet ball milled for several hours and surfactants like Triton-X small fillers (2 / 4 mm long rod-shaped) were made for in vitro testing. In order to verify the biocompatibility of HAp powders, cytotoxicity evaluation was carried out in RAW macrophage like cell line media for an incubation period of 72 h. The cell attachment studies on HAp compacts show an excellent affinity between cells and compact surface. These results proved high biocompatibility of HAp powders obtained fromdifferent biosources for tissue engineering applications.

    • Author Affiliations


      Sudip Mondal1 Rajashree Bardhan1 Biswanath Mondal1 Apurba Dey2 Sudit S Mukhopadhyay2 Syamal Roy3 Rajan Guha3 Koushik Roy3

      1. Centre for Advanced Materials Processing, CSIR-Central Mechanical Engineering Research Institute, Durgapur 713 209, India
      2. Department of Biotechnology, National Institute of Technology, Durgapur 713 209, India
      3. CSIR-Indian Institute of Chemical Biology, Kolkata 700 032, India
    • Dates

  • Bulletin of Materials Science | News

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      Posted on October 12, 2020

      Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
      Chemical Sciences 2020

      Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
      Physical Sciences 2020

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

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