• Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/boms/035/04/0683-0691

    • Keywords

       

      Hydroxyapatite; biomaterials; sintering; tissue engineering; cytotoxicity.

    • Abstract

       

      In the present study, hydroxyapatite (HAp) is synthesized from different biosources like eggshell, fish scale and bovine bone in a cost effective and ecofriendly way. HAp materials were synthesized from eggshell by wet precipitation method whereas thermal decomposition method was applied in case of fish scale and bovine bone. The phase purity and crystallinity of different calcined HAp powder were determined by XRD and FTIR analyses. The thermogravimetric analysis was carried out to show thermal stability of HAp powder. Average grain sizes of sintered samples were in submicron range. The morphology of the powders were observed under scanning electron microscopy (SEM). The dried powders were wet ball milled for several hours and surfactants like Triton-X small fillers (2 / 4 mm long rod-shaped) were made for in vitro testing. In order to verify the biocompatibility of HAp powders, cytotoxicity evaluation was carried out in RAW macrophage like cell line media for an incubation period of 72 h. The cell attachment studies on HAp compacts show an excellent affinity between cells and compact surface. These results proved high biocompatibility of HAp powders obtained fromdifferent biosources for tissue engineering applications.

    • Author Affiliations

       

      Sudip Mondal1 Rajashree Bardhan1 Biswanath Mondal1 Apurba Dey2 Sudit S Mukhopadhyay2 Syamal Roy3 Rajan Guha3 Koushik Roy3

      1. Centre for Advanced Materials Processing, CSIR-Central Mechanical Engineering Research Institute, Durgapur 713 209, India
      2. Department of Biotechnology, National Institute of Technology, Durgapur 713 209, India
      3. CSIR-Indian Institute of Chemical Biology, Kolkata 700 032, India
    • Dates

       
  • Bulletin of Materials Science | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2017-2019 Indian Academy of Sciences, Bengaluru.