• Degradation and miscibility of poly(DL-lactic acid)/poly(glycolic acid) composite films: Effect of poly(DL-lactic-co-glycolic acid)

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      https://www.ias.ac.in/article/fulltext/boms/035/04/0575-0578

    • Keywords

       

      Polymers; composite materials; thin films; microstructure; compatibility.

    • Abstract

       

      The in vitro degradation behaviour of poly(glycolic acid) (PGA) and its composite films containing poly(DL-lactic acid) (PDLLA) and poly(DL-lactic-co-glycolic acid) (PDLGA) were investigated via mass loss, scanning electron microscopy (SEM) and differential scanning calorimetry (DSC). All the films were prepared by solution casting, using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as the solvent. Since the degradation rate of PDLLA is lower than that of PGA, those of the PDLLA/PGA composite films decreased. As a compatibilizer, PDLGA improved the compatibility and hydrolytic stability of PDLLA/PGA composite films. Changes in the composite films indicate that this kind of PGA-based composite biomaterial may be applicable to device design for clinical application in the future.

    • Author Affiliations

       

      Zhigang Ma1 Na Zhao1 Chengdong Xiong2

      1. School of Chemical and Material Engineering, Huangshi Institute of Technology, Huangshi, 435003, P. R. China
      2. Chengdu Organic Chemicals Co. Ltd., Chinese Academy of Sciences, Chengdu 610041, P. R. China
    • Dates

       
  • Bulletin of Materials Science | News

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