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      https://www.ias.ac.in/article/fulltext/boms/035/03/0481-0487

    • Keywords

       

      Chitosan; dry heat; mass transport; membranes; water sorption.

    • Abstract

       

      The present work deals with the study of estradiol permeation in chitosan membranes. A fractional factorial design was built for the determination of the main factors affecting estradiol permeation. The independent factors analysed were: concentration of chitosan, concentration of cross-linking agent, cross-linking time and thermal treatment. It was found that concentration of chitosan and cross-linking time significantly affected the response. The effects of thermal treatment and concentration of cross-linking agent were not significant. An optimization process based on response surface methodology was carried out in order to develop a statistical model which describes the relationship between active independent variables and estradiol flux. This model can be used to find out a combination of factor levels during response optimization. Possible options for response optimization are to maximize, minimize or move towards a target value.

    • Author Affiliations

       

      Luciano Mengatto1 María I Cabrera1 2 Julio A Luna1

      1. Laboratorio de Química Fina, INTEC – UNL – CONICET, Centro Científico Tecnológico, Ruta Nacional 168 Paraje El Pozo, Santa Fe, Argentina
      2. Since deceased
    • Dates

       
  • Bulletin of Materials Science | News

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      Posted on July 25, 2019

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