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      https://www.ias.ac.in/article/fulltext/boms/024/04/0431-0434

    • Keywords

       

      Cholesterol; gel method; organic solvents; micro-topographical studies; layered growth.

    • Abstract

       

      Cholesterol (C27H46O) is the most abundant and best-known steroid in the animal kingdom. The in vitro crystallization of this important biomaterial has been attempted by few researchers. Here we are reporting crystallization of pure cholesterol monohydrate crystals in gel medium. It is found that the morphology of the crystals depends on various parameters. The effect of solvent has been studied in detail. The different morphologies observed are fibrous, needle, platelet, dendrite etc. Micro topographical studies have been made and it is found that the crystals grow, at least in the last stage, by spreading of layers. However, at initial stage microcrystals formed and developed into dendrite or needle forms. These one-dimensional crystals developed into platelets and finally thickened. Further studies reveal that micro impurities play a vital role in the development of these crystals as seen by dissolution figures on the crystals. These crystals are characterized by using the XRD and IR spectroscopic methods.

    • Author Affiliations

       

      Anit Elizabeth1 Cyriac Joseph1 M A Ittyachen1

      1. School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam 686 560, India
    • Dates

       
  • Bulletin of Materials Science | News

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