Changes in protein concentration due to electrical stimulation have been investigated at different time intervals in cockroach ventral nerve cord. Significant increase in total protein concentration was observed at 15 min interval of stimulation. Increase in protein concentration was also observed in ventral nerve cords incubated with exogenous glucose. Microdisc Polyacrylamide gel electrophoresis at 15 min interval has revealed an increase in low molecular weight protein fractions in nerve cords from stimulated group. The data clearly depict the changes in protein due to electrical stimulation stress.