The dynamic nature of the galls evoked by species ofMeloidogyne (root-knot nematode) involves many hypersensitive reactions. Energy relations in the galls of the suscep-tible hosts reflect the combat capabilities centering around functional resistance. Factors associated with resistance are indicated. The futurology of the problem of containing the infection is discussed. Chemotherapy consisting of imparting resistance in susceptible hosts is suggested, to achieve success in agricultural economy. Electrophysiological relations of pathogenesis and the future implications of these studies in the understanding of th6 disease are indicated.