• Evaluation of warfarin againstTatera indica andMeriones hurrianae

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      https://www.ias.ac.in/article/fulltext/anml/091/05/0463-0468

    • Keywords

       

      T. indica ; M. hurrianae ; oral toxicity; no-choice tests; base-line; susceptibility; palatability; warfarin

    • Abstract

       

      Warfarin was evaluated in laboratory against Indian gerbil,Tatera indica and desert gerbil,Meriones hurrianae. Chronic LD50 for the two species was found to be 4 × 19·1 and 4 × l5·9mg/kg respectively. Feeding for 14 days on 0·025% warfarin treated bait provided complete kill in the gerbils but the poisoned bait was less palatable than the plain bait. A period of 18 and 19 days feeding on 0·025% waifarin bait was found suitable to detect resistance to warfarin amongT. indica andM. hurrianae respectively.

    • Author Affiliations

       

      R P Mathur1 Ishwar Prakash1

      1. Coordinating and Monitoring Centre for Rodent Research and Training, Central Arid Zone Research Institute, Jodhpur - 342 003, India
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