University of Mysore, Mysuru
N B Ramachandra joined the University of Mysore as a Lecturer in Zoology in 1992. He was instrumental in starting the master’s course in Genetics there, and is now the Chairman of the Department of Studies in Genetics and Genomics, University of Mysore. His research interests are in the field of Drosophila and human genetics, evolution and genomics. His significant contributions include evidences for adaptive genome evolution in Drosophila, identification of SNPs and CNVs for several diseases, advanced grandmother age as a cause for Down’s syndrome, identification of a new recombining region, PAR3, and establishment of University of Mysore Genome Centre database. He has published more than 200 research papers and delivered more than 200 invited lectures. His work has been recognised by many awards. In 2017, he was elected as a Fellow of the Indian Academy of Sciences, Bengaluru.
SESSION 3A: Inaugural lectures by Fellows/Associates
S Ananthakrishnan, Savitribai Phule Pune University, Pune
Impact of copy number variations in genome organization, evolution and diseases
The speaker and his group have performed genome-wide genotyping by CNV microarray analysis and identified 44,109 CNVs from 1,715 genomes across 12 populations to unravel genomic variations in human genome organization, evolution and some complex diseases. Some of their findings, including the identification of the complexity in chromosome organization, genome organizational plasticity and the proposal of human new migration routes, establishment of the previously identified X chromosome Transposed Region (XTR) in Y-chromosome as pseudoautosomal region 3 (PAR3), and identification of the type 2 diabetes mellitus disease risk genes, Parkinson Disease risk genes and Asthma susceptibility marker genes under CNV burden in normal cohorts, will be discussed with reference to the role of CNVs in the genomic variations.