• Mesoscopic biology

    • Fulltext

       

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      Permanent link:
      http://www.ias.ac.in/article/fulltext/pram/058/02/0439-0442

    • Keywords

       

      Gene expression; DNA; single molecule physics; genetic networks; optical tweezers; single molecule detection.

    • Abstract

       

      In this paper we present a qualitative outlook of mesoscopic biology where the typical length scale is of the order of nanometers and the energy scales comparable to thermal energy. Novel biomolecular machines, governed by coded information at the level of DNA and proteins, operate at these length scales in biological systems. In recent years advances in technology have led to the study of some of the design principles of these machines; in particular at the level of an individual molecule. For example, the forces that operate in molecular interactions, the stochasticity involved in these interactions and their spatio-temporal dynamics are beginning to be explored. Understanding such design principles is opening new possibilities in mesoscopic physics with potential applications.

    • Author Affiliations

       

      G V Shivashankar1

      1. National Center for Biological Sciences, Tata Institute of Fundamental Research, UAS-GKVK Campus, Bangalore 560 065, India
  • Pramana – Journal of Physics | News

    • Proceedings of the International Workshop/Conference on Computational Condensed Matter Physics and Materials Science
      (IWCCMP-2015)

      Posted on November 27, 2015

      Guest Editors: Anurag Srivastava, C. S. Praveen,
      H. S. Tewari

© 2017 Indian Academy of Sciences, Bengaluru.